Any way to enlarge the work area pixel size?

See the attached capture. On a 1600x1200 monitor the size of this GUI makes using a mouse on them tedious. Same applies to the effects window.  Is there a way to enlarge this in terms of pixel size?  I'm not talking about expanding the time line --that just helps it horizontally.  My problem is with the pixel size itself, especially grabbing the tiny yellow lines and moving them with any amount of precision.  Not only does it cause me eye strain, the mouse is barely sensitive enough to work at this pixel size.

Thanks in advance!